Guoyong Xu（胥国勇）

Education

Sep 2007 – Jul 2012 Tsinghua University, China Ph.D.
Sep 2003 – Jul 2007 Nankai University, China B.S.

Working Experience

Jan 2018 – Now Wuhan University, China Professor
Aug 2013 – Dec 2017 Duke University, U.S.A. Postdoc
Jul 2012 – Jul 2013 Tsinghua University, China Postdoc
Oct 2010 – Jul 2013 Tsinghua University, China College Counselor

教育经历

2003年9月– 2007年7月 南开大学生命科学学院 学士
2007年9月– 2012年7月 清华大学生命科学学院 博士

工作经历

2010年10月– 2013年7月清华大学生命科学学院 医药实验班本科辅导员
2012年7月– 2013年7月清华大学生命科学学院 博士后
2013年8月– 2017年12月杜克大学生物系 博士后
2018年1月起武汉大学高等研究院 教授、博士生导师

Representative Research Articles

8. Luo, Ming; Zhu, Sitao; Dang, Hua; Wen, Qing; Niu, Ruixia; Long, Jiawei; Wang, Zhao; Tong, Yongjia; Ning, Yuese; Yuan, Meng; Xu, Guoyong*; Genetically-encoded targeted protein degradation technology to remove endogenous condensation-prone proteins and improve crop performance, Nature Communications, 2025, 01(25), https://doi.org/10.1038/s41467-025-56570-x
7. Tang, Zhijuan#; Shi, Shaosong#; Niu, Ruixia#; Zhou, Yulu; Wang, Zhao; Fu, Rongrong; Mou, Rui; Chen, Suming; Ding, Pingtao; Xu, Guoyong*; Alleviating protein-condensation-associated damage at the endoplasmic reticulum enhances plant disease tolerance, Cell Host & Microbe, 2024, 07(24), https://doi.org/10.1016/j.chom.2024.07.013
6. Tian, Jingjing#; Tang, Zhijuan#; Niu, Ruixia#; Zhou, Yulu; Yang, Dan; Chen, Dan; Luo, Ming; Mou, Rui; Yuan, Meng*; Xu, Guoyong*; Engineering disease-resistant plants with alternative translation efficiency by switching uORF types through CRISPR, Science China Life Sciences, 2024, 04(24), https://doi.org/10.1007/s11427-024-2588-9
5. Zhou, Yulu#; Niu, Ruixia#; Tang, Zhijuan#; Mou, Rui; Wang, Zhao; Zhu, Sitao; Yang, Hongchun; Ding, Pingtao; Xu, Guoyong*; Plant HEM1 specifies a condensation domain to control immune gene translation, Nature Plants, 2023, 01(23), https://doi.org/10.1038/s41477-023-01355-7
4. Chen, Tianyuan#; Xu, Guoyong#*; Mou, Rui; Greene, George H.; Liu, Lijing; Motley, Jonathan; Dong, Xinnian*; Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein, Cell Host & Microbe, 2023, 01(23), https://doi.org/10.1016/j.chom.2023.01.014
3. Xu, Guoyong#; Greene, George H.; Yoo, Heejin#; Liu, Lijing; Marqués, Jorge; Motley, Jonathan; Dong, Xinnian*. Global translational reprogramming is a fundamental layer of immune regulation in plants. Nature, 04/2017. https://doi.org/10.1038/nature22371
2. Xu, Guoyong#; Yuan, Meng#; Ai, Chaoren; Liu, Lijing; Zhuang, Edward; Karapetyan, Sargis; Wang, Shiping; Dong, Xinnian*. uORF-mediated translation allows engineered plant disease resistance without fitness cost. Nature, 04/2017. https://doi.org/10.1038/nature22372
1. Xu, Guoyong#; Wang, Shanshan#; Han, Shaojie; Xie, Ke; Wang, Yan; Li, Jinlin; Liu, Yule*. Plant Bax Inhibitor-1 interacts with ATG6 to regulate autophagy and programmed cell death. Autophagy, 07/2017. https://doi.org/10.1080/15548627.2017.1320633